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| 04:00 Racing Club de Avellaneda – Boca Juniors 1:1 | 3.32 | 2.98 | 2.40 | X2 | 0-1 | U |
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| 04:30 Pumas UNAM – Club Necaxa 1:1 | 1.91 | 3.56 | 3.72 | 1 | 1-0 | U |
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| 04:45 Junior de Barranquilla – Once Caldas 1:1 | 1.89 | 3.40 | 4.00 | 1 | 1-0 | U |
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| 15:45 Sabah – Star City Kangar 3:1 | 2.28 | 3.28 | 2.81 | 1 | 1-0 | U |
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| 17:30 Kokand 1912 – Buxoro 1:1 | 2.72 | 2.98 | 2.73 | X2 | 0-1 | U |
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| 18:00 Isloch – Dinamo Minsk 1:0 | 3.27 | 3.06 | 2.30 | 1X | 1-3 | O |
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| 18:30 Tractor Tabriz – Persepolis 1:0 | 2.29 | 3.08 | 2.96 | X2 | 0-1 | U |
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| 18:30 Vardar – Sileks 4:1 | 1.63 | 3.36 | 5.25 | X2 | 0-1 | U |
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| 19:00 Botosani – Csikszereda Miercurea Ciuc 1:0 | 1.64 | 3.88 | 4.90 | 1 | 1-0 | U |
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| 19:30 Botev Vratsa – Botev Plovdiv 1:0 | 3.64 | 3.12 | 2.09 | 2 | 0-1 | U |
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| 19:30 Verl – Hamburger 0:3 | 5.89 | 5.05 | 1.43 | 2 | 1-3 | O |
| 19:30 VSG Altglienicke – VfL Wolfsburg : | 14.70 | 7.90 | 1.14 | 2 | 1-3 | O |
| 19:30 Wurzburger Kickers – 1. Koln 1:2 | 8.70 | 5.45 | 1.30 | 1X | 2-0 | U |
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| 19:30 Kheybar Khorramabad – Paykan : | 2.58 | 2.56 | 3.18 | 1X | 1-0 | U |
| 19:30 Malavan – Fajr Sepasi : | 2.17 | 3.02 | 3.14 | 1X | 1-0 | U |
| 19:30 Zob Ahan – Mes Shahr-e Babak 1:1 | 2.07 | 2.99 | 3.42 | 1X | 1-0 | U |
| 20:00 Gol Gohar – Chador Malu : | 2.49 | 3.04 | 2.63 | 1X | 1-0 | U |
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| 20:00 Bologna 1909 – Lazio : | 2.31 | 3.32 | 3.54 | X2 | 0-1 | U |
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| 20:10 Neom SC – Al-Qadisiyah : | 5.03 | 4.36 | 1.56 | 2 | 1-2 | O |
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| 20:30 Brondby – Silkeborg : | 1.43 | 4.75 | 6.34 | 1 | 2-1 | O |
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| 20:30 Sanat Naft Abadan – Foolad Khuzestan : | 4.13 | 3.15 | 1.82 | X2 | 1-2 | U |
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| 20:30 Farense – Felgueiras 1932 : | 2.10 | 3.04 | 3.74 | 1X | 2-1 | U |
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| 20:30 Skendija – Struga Trim & Lum : | 1.71 | 3.32 | 4.64 | 1 | 1-0 | U |
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| 20:30 Celta Fortuna – Andorra Andorra la Vella : | 3.38 | 3.50 | 2.17 | X2 | 0-1 | U |
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| 20:30 Malmo – Djurgardens : | 2.61 | 3.50 | 2.48 | 1X | 2-1 | O |
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| 20:30 IFK Varnamo – Landskrona BoIS : | 2.31 | 3.40 | 2.89 | 1X | 1-0 | U |
| 20:30 Ostersunds – Ljungskile : | 1.92 | 3.52 | 3.72 | 1 | 2-1 | U |
| 20:35 IFK Norrkoping – Falkenbergs : | 1.58 | 4.15 | 5.03 | 1 | 2-1 | O |
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| 21:00 Torpedo-BelAZ – Dnepr Mogilev : | 1.74 | 3.48 | 4.86 | 1 | 2-1 | O |
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| 21:00 Baltika Kaliningrad – Rubin Kazan : | 2.09 | 3.38 | 4.14 | X2 | 1-2 | U |
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| 21:00 Osasuna – Levante UD : | 1.89 | 3.70 | 4.62 | X2 | 1-2 | U |
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| 21:30 PSV Eindhoven II – Oss : | 1.66 | 4.20 | 4.30 | X2 | 1-2 | O |
| 21:30 Utrecht II – Heracles Almelo : | 4.88 | 4.33 | 1.57 | 1X | 2-1 | O |
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| 21:30 Al-Ittihad Jeddah – Al Hazem Rass : | 1.50 | 4.50 | 5.55 | 1 | 2-1 | O |
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| 21:45 Lokomotiv Plovdiv – Arda Kardzhali : | 3.78 | 3.05 | 2.08 | X2 | 1-2 | U |
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| 22:00 Otelul Galati – Arges Pitesti : | 2.40 | 2.69 | 3.50 | X2 | 1-2 | U |
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| 22:00 Kocaelispor – Amedspor : | 2.27 | 3.34 | 3.43 | 1X | 1-0 | U |
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| 22:00 Sivasspor – Manisa : | 2.00 | 3.32 | 3.36 | X2 | 0-1 | U |
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| 22:15 Stade de Reims – Annecy : | 1.84 | 3.70 | 3.93 | X2 | 1-2 | U |
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| 22:15 Hallescher – Schalke 04 : | 9.05 | 5.50 | 1.29 | 2 | 1-2 | O |
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| 22:15 Roma – Fiorentina : | 1.75 | 3.96 | 5.23 | X2 | 1-2 | O |
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| 22:30 Fulham – Chelsea : | 4.21 | 3.98 | 1.90 | 2 | 1-2 | O |
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| 22:30 Club Nacional Asuncion – Sportivo Luqueno : | 1.78 | 3.57 | 4.36 | 1 | 2-1 | U |
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| 22:45 Breidablik UBK – Knattspyrnufelagid Fram : | 2.50 | 3.96 | 2.34 | X2 | 1-3 | O |
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| 22:45 Feirense – Porto II : | 2.08 | 3.18 | 3.60 | X2 | 1-2 | U |
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| 23:00 Malaga – Deportivo de A Coruna : | 2.51 | 3.09 | 3.40 | 1X | 2-1 | U |
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| 23:00 Granada – Mallorca : | 3.14 | 3.10 | 2.49 | X2 | 1-2 | U |
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| 01:00 Club Libertad – Club Sportivo San Lorenzo : | 1.33 | 5.00 | 8.45 | 1 | 3-0 | U |
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| 01:30 Club Atletico Tigre – Central Cordoba de Santiago : | 1.66 | 3.44 | 6.26 | 1X | 2-1 | U |
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| 02:30 Botafogo de Futebol e Regatas – Clube Atletico Paranaense : | 2.47 | 3.22 | 3.06 | 1X | 1-0 | U |
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| 02:30 Charleston Battery – Miami : | 1.33 | 4.95 | 6.88 | 1 | 2-1 | O |
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| 03:00 Everton de Vina del Mar – Universidad de Concepcion : | 1.79 | 3.40 | 4.03 | X2 | 1-2 | O |
